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  • Based on the official NCLEX-RN exam guidelines
  • Updated for June 2025

NCLEX-RN Practice Questions: Safety & Infection Control (2025)

Welcome to the second practice test on Safety and Infection Control, one of the subcategories of the Client Need, Safe and Effective Care Environment. When you sit for your NCLEX, you can expect about 12% of the test items from Safe and Effective Care Environment, anywhere from 9 to 31 questions, depending on how long your examination is. (There will be 75-265 questions.) The content covers: Accident/Error/Injury Prevention; Ergonomic Principles; Handling Hazardous and Infectious Materials; Home Safety; Reporting Incidents/Variances, Standard Precautions/Transmission-Based Precautions/Surgical Asepsis, Safe Use of Equipment, and Use of Restraints and Safety Devices. This practice test includes questions about home safety, nursing care outside acute settings, client identification, hand hygiene, and medication issues. Start this test whenever you’re ready. If you leave any test before it’s completed, it will remind you where you left off when you return. Read each question carefully and try to think of the answer before looking at the options. Remember to select the BEST choice. If you’re not sure, click on the Hint button under the fourth option to get a clue. When you select the correct response, you’ll go the next question. If you make a mistake, an explanation will immediately pop up. Each time you take a practice test, the questions and options are shuffled into a different random order. Both of these techniques have been proven to reinforce your learning.
  • Perfect for nursing students and professionals preparing for the NCLEX exam
  • Triple-checked for accuracy by nursing experts
What you need to know
4.42 out of 5 • 19 votes.
Reviewed by Winona Suzanne Ball, Nursing Adviser, RN | MHS, Governors State University, IL, Full member of the American Nurses Association.
What to expect on the official exam
75-145

questions

5 hours

exam length

Pass/Fail

exam type

Computer Adaptive

scoring format

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