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  • Based on the official NCLEX-PN exam guidelines
  • Updated for June 2025

NCLEX-PN Safety & Infection Control Practice Test

Welcome to the NCLEX-PN practice test for Safety and Infection Control, a subcategory of the Client Need, Safe and Effective Care Environment. The LPN/VN plays an essential role in protecting clients and team members from health and environmental hazards. Between 10 to 16% of NCLEX-PN test items will be about these important nursing responsibilities in various settings. The content in Safety and Infection Control includes accident and injury prevention, emergency response plan, ergonomic principles, handling hazardous and infectious materials, home safety, incident and variance reports, and proper use of restraints and safety devices. Standard precautions, transmission-based precautions, and surgical asepsis are also included in this section. Questions in this practice test cover disease transmission, preventing infections, fire safety, hand hygiene, client allergies, and CDC precautions. Start this test whenever you’re ready. If you leave any test before it’s completed, it will remind you where you left off when you return. Read each question carefully and try to think of the answer before looking at the options. Remember to select the BEST choice. If you’re not sure, click on the Hint button under the fourth option to get a clue. When you select the correct response, you’ll go the next question. If you make a mistake, an explanation will immediately pop up. Each time you take a practice test, the questions and options are shuffled into a different random order. Both of these techniques have been proven to reinforce your learning.
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  • Perfect for nursing students and professionals preparing for the NCLEX exam
  • Triple-checked for accuracy by nursing experts
What you need to know
Reviewed by Winona Suzanne Ball, Nursing Adviser, RN | MHS, Governors State University, IL, Full member of the American Nurses Association.
What to expect on the official exam
75-145

questions

5 hours

exam length

Pass/Fail

exam type

Computer Adaptive

scoring format

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